Immune Reconstitution Bone Loss Exacerbates Bone Degeneration Due to Natural Aging in a Mouse Model.

M Neale WeitzmannDaiana WeissTatyana VikulinaSusanne Roser-PageKanglun YuMeghan E McGee-LawrenceChia Ling TuWenhan ChangIghovwerha Ofotokun

Published in: The Journal of infectious diseases (2022)

Immune reconstitution bone loss in the trabecular compartment is permanent and further exacerbates bone loss due to natural aging. If validated in humans, interventions to limit IRBL may be important to prevent fractures in aging PWH.

Keyphrases

bone loss
mouse model
bone mineral density
physical activity
body composition