Calcium-binding motif-mediated binding of redundant calcium offers a chimeolysin enhanced bactericidal activity and extended host range under physiological conditions.

Minghui JiaWanli ZhouDehua LuoHeng XueFen HuXiaomei ZhangZirong ZhaoMingyue ZhongXinfeng LiJin HeHongping WeiHang Yang

Published in: The Journal of antimicrobial chemotherapy (2023)

The present data collectively showed that physiological calcium improves the bactericidal activity and host range of ClyF, making it a promising candidate for the treatment of infections caused by multiple staphylococci and streptococci.

Keyphrases

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transcription factor
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smoking cessation