High rates of (treated) hypothyroidism among chronic migraine patients consulting a specialized headache clinic: are we missing something?

Marcelo FilipchukJesica GassmannTatiana Castro ZamparellaMaria Cecilia TibaldoMariela CarpinellaPablo Sesto TagliaviniPablo ScarnatoMaria Teresa GoicocheaOsvaldo BrueraDiego Martin Conci MagrisMarco Lisicki

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2021)

Alterations of neuronal metabolism, deficient calcitonin release, or focal inflammation causing local hormonal deactivation might explain why hypothyroidism, in spite of levothyroxine replacement therapy, is associated with migraine chronification. Further studies evaluating these factors are warranted.

Keyphrases

replacement therapy
newly diagnosed
smoking cessation
end stage renal disease
ejection fraction
oxidative stress
palliative care
peritoneal dialysis
metabolic syndrome