Repurposing of antidiabetics as Serratia marcescens virulence inhibitors.

Wael A H HegazyMaan T KhayatTarek S IbrahimMahmoud YounsRasha MosbahWafaa E Soliman

Published in: Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] (2021)

The downregulation of virulence genes was not enough to show anti-virulence activities. Hindering of QS receptors may play a crucial role in diminishing bacterial virulence.

Keyphrases

pseudomonas aeruginosa
escherichia coli
staphylococcus aureus
antimicrobial resistance
biofilm formation
cystic fibrosis
cell proliferation
signaling pathway
genome wide
transcription factor