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Similar usage of T-cell receptor β-chain between tumor and adjacent normal tissue in hepatocellular carcinoma.

Jie-Zuan YangShao-Yan XuDang-Sheng XiaoJin-You LiXiu-Yuan JinDong Yan
Published in: Cancer medicine (2024)
This study provided a large amount of information about the TCR lineage in HBV-associated HCC, laying the foundation for further research. In addition, the fact that the immune repertoire (TRBV CDR3) hardly differs between tumor and adjacent normal tissue provides a new clue for exploring the mechanism of the liver as an organ with immune privileges.
Keyphrases
  • hepatitis b virus
  • regulatory t cells
  • heat stress
  • single cell
  • immune response
  • health information
  • liver failure
  • binding protein