Similar usage of T-cell receptor β-chain between tumor and adjacent normal tissue in hepatocellular carcinoma.
Jie-Zuan YangShao-Yan XuDang-Sheng XiaoJin-You LiXiu-Yuan JinDong YanPublished in: Cancer medicine (2024)
This study provided a large amount of information about the TCR lineage in HBV-associated HCC, laying the foundation for further research. In addition, the fact that the immune repertoire (TRBV CDR3) hardly differs between tumor and adjacent normal tissue provides a new clue for exploring the mechanism of the liver as an organ with immune privileges.