Genetic and Environmental Influences on the Correlations between Traits of Metabolic Syndrome and CKD.
Xu ChenIstiak BhuiyanRalf Kuja-HalkolaPatrik K E MagnussonPer O SvenssonPublished in: Clinical journal of the American Society of Nephrology : CJASN (2019)
Both genes and environment contribute to the correlation between metabolic syndrome and eGFR-defined CKD. The genetic contribution is particularly important to the correlation between abdominal obesity and eGFR.
Keyphrases
- metabolic syndrome
- genome wide
- small cell lung cancer
- insulin resistance
- epidermal growth factor receptor
- chronic kidney disease
- tyrosine kinase
- dna methylation
- uric acid
- copy number
- cardiovascular risk factors
- type diabetes
- adipose tissue
- risk assessment
- cardiovascular disease
- human health
- skeletal muscle
- body mass index
- climate change