Treatment and Survival of Malignant Extracranial Germ Cell Tumours in the Paediatric Population: A Systematic Review and Meta-Analysis.

Caroline C C HulskerIssam El MansoriMarta FioccoJózsef ZsirosMarc H W WijnenLeendert H J Looijenga Annelies M C Mavinkurve-GroothuisAlida F W van der Steeg

Published in: Cancers (2021)

This review describes the heterogeneous nature of GCTs in different anatomical locations, impacting on stage at presentation, treatment modalities used and survival data. Despite this heterogeneity, in line with the current developmental biology-based classification system, subpopulations can be defined which have an inferior EFS and OS and where future research and more individualised treatment would help to improve survival.

Keyphrases

emergency department
intensive care unit
free survival
smoking cessation
deep learning
data analysis