BAPTA, a calcium chelator, neuroprotects injured neurons in vitro and promotes motor recovery after spinal cord transection in vivo.

Kyu-Ree KangJin KimBokyeong RyuSeul-Gi LeeMin-Seok OhJieun BaekXiaoping RenSergio CanaveroC-Yoon KimHyung Min Chung

Published in: CNS neuroscience & therapeutics (2021)

This study shows for the first time that local/immediate application of Ca++ chelator BAPTA is strongly neuroprotective after severe spinal cord injury.

Keyphrases

spinal cord
spinal cord injury
neuropathic pain
early onset
brain injury