Synthesis of Dibenzotropones by Alkyne-Carbonyl Metathesis.

Maryam SobhaniAnna FreyAndre RettmannRichard ThomAlexander Villinger Peter Ehlers Peter Langer

Published in: The Journal of organic chemistry (2021)

Dibenzocycloheptanones (dibenzotropones) were prepared by Brønsted acid mediated intramolecular alkyne-carbonyl metathesis (ACM) reactions. The cyclization precursors are readily available by Sonogashira reaction of 2-bromobenzoyl chloride with terminal alkynes, followed by Suzuki reactions with benzaldehydes. The ACM reactions are highly modular and atom economic and allow for the construction of two regioisomeric series of dibenzotropones.

Keyphrases

molecular dynamics
electron transfer
energy transfer
visible light