Decreased occurrence of ketoacidosis and preservation of beta cell function in relatives screened and monitored for type 1 diabetes in Australia and New Zealand.
John M WentworthHelena OakeyMaria E CraigJennifer J CouperFergus J CameronElizabeth A DavisAntony R LaffertyMark HarrisBenjamin J WheelerCraig A JefferiesPeter G ColmanLeonard C HarrisonPublished in: Pediatric diabetes (2022)
T1D autoantibody screening and metabolic monitoring of older children and young adults in Australia and New Zealand, by enabling pre-clinical diagnosis when beta cell reserve is greater, confers protection from DKA. These clinical benefits support ongoing efforts to increase screening activity in the region and should facilitate the application of emerging immunotherapies.