Disagreement in normative IGF-I levels may lead to different clinical interpretations and GH dose adjustments in GH deficiency.
A J VarewijckA J van der LelyS J C M M NeggersL J HoflandJoseph A M J L JanssenPublished in: Clinical endocrinology (2017)
IGF-I Z-scores in 102 GH-deficient subjects differed significantly when normative data from two different sources were used. In daily clinical practice, this would most likely have led to different clinical interpretations and GH dose adjustments.