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The combined restoration of miR-424-5p and miR-142-3p effectively inhibits MCF-7 breast cancer cell line via modulating apoptosis, proliferation, colony formation, cell cycle and autophagy.

Narges DastmalchiReza SafaralizadehSeyed Mahdi Banan KhojastehMahdi Abdoli ShadbadMohammad Ali HosseinpourfeiziShirin AzarbarzinAli RajabiBehzad Baradaran
Published in: Molecular biology reports (2022)
The combined restoration of miR-424-5p and miR-142-3p is more effective in inhibiting MCF-7 breast cancer development than monotherapies with miR-424-5p and miR-142-3p.
Keyphrases
  • cell cycle
  • signaling pathway
  • endoplasmic reticulum stress
  • breast cancer cells
  • cell proliferation
  • oxidative stress
  • cell death
  • pi k akt
  • cell cycle arrest
  • young adults