Early Evaluation and Monitoring of Critical Patients with Acute Respiratory Distress Syndrome (ARDS) Using Specific Genetic Polymorphisms.
Florin G HorhatFuat GundogduLaurentiu V DavidEugen S BoiaLaurentiu PirteaRazvan HorhatAlexandru Cucui-CozmaIoana CiucaMircea DiaconuRazvan NituMonica LickerDelia I HorhatAlexandru Florin RogobeteMarius L MoiseCalin TataruPublished in: Biochemical genetics (2017)
A high percentage of critical patients are found to develop acute respiratory distress syndrome (ARDS). Several studies have reported high mortality rates in these cases which are most frequently associated with multiple organ dysfunctions syndrome. Lately, many efforts have been made to evaluate and monitor ARDS in critical patients. In this regard, the assessment of genetic polymorphisms responsible for developing ARDS present as a challenge and are considered future biomarkers. Early detection of the specific polymorphic gene responsible for ARDS in critically ill patients can prove to be a useful tool in the future, able to help decrease the mortality rates in these cases. Moreover, identifying the genetic polymorphism in these patients can help in the implementation of a personalized intensive therapy scheme for every type of patient, based on its genotype.
Keyphrases
- acute respiratory distress syndrome
- extracorporeal membrane oxygenation
- mechanical ventilation
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- healthcare
- primary care
- stem cells
- cardiovascular disease
- intensive care unit
- type diabetes
- quality improvement
- coronary artery disease
- case report
- cardiovascular events
- risk factors
- current status