Lactated Ringers, albumin and mannitol as priming during cardiopulmonary bypass reduces pulmonary edema in rats compared with hydroxyethyl starch.
Anne M BeukersAnoek L I van LeeuwenRoselique IbelingsAnita M Tuip-de BoerCarolien S E BulteSusanne EberlCharissa E van den BromPublished in: Intensive care medicine experimental (2024)
CPB priming with LR, albumin and mannitol resulted in less pulmonary edema, renal injury, inflammation and glycocalyx degradation compared to 6% HES. Furthermore, it enhanced hemodynamic stability compared with HES. Further research is needed to explore the specific role of albumin as a beneficial additive in CPB priming.
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