PAD4-Induced NETosis Via Cathepsin G-Mediated Platelet-Neutrophil Interaction in ChAdOx1 Vaccine-Induced Thrombosis.
Roberto CarnevaleMartina LeopizziMarcello DominiciGiulia d'AmatiSimona BartimocciaCristina NocellaVittoria CammisottoAlessandra D'AmicoValentina CastellaniFrancesco BarattaAlessia BertelliAlessio ArriviDanilo ToniManuela De MichelePasquale PignatelliRossella MarcucciFrancesco VioliPublished in: Arteriosclerosis, thrombosis, and vascular biology (2023)
Patients with VITT display enhanced thrombogenesis by PAD4-mediated NETs formation via cathepsin G-mediated platelet/neutrophil interaction.