A Feasibility Study of Patients with Major Depression and Substance Use Disorders: Vortioxetine as Maintenance Treatment.

Ignacio Basurte-Villamor Pablo Vega Villaamil Carlos RonceroJosé Martínez-RagaLara Grau-LópezLourdes AguilarMarta TorrensNestor Szerman

Published in: Neuropsychiatric disease and treatment (2022)

Vortioxetine was effective in clinical practice for alleviating depressive symptoms and functional impairment, and in improving cognitive and executive functions and disease severity in patients with MDD and SUD. Moreover, the treatment with vortioxetine favored a reduction in substance use and the severity of the SUDs.

Keyphrases

major depressive disorder
depressive symptoms
clinical practice
bipolar disorder
physical activity
sleep quality
smoking cessation