Distribution of type 2 biomarkers and association with severity, clinical characteristics and comorbidities in the BREATHE real-life asthma population.
Laurits FrøssingDitte K KleinMorten HvidtfeldtNicolai OblingGunilla TelgJonas S ErjefältUffe BødtgerCeleste M PorsbjergPublished in: ERJ open research (2023)
Severe asthma is more commonly associated with activation of several T2 pathways, indicating that treatments targeting severe asthma may need to act more broadly on T2 inflammatory pathways. Implementation of airway inflammometry in clinical care is of paramount importance, as the best treatable trait is otherwise is overlooked in a large proportion of patients irrespective of disease severity.
Keyphrases
- healthcare
- end stage renal disease
- newly diagnosed
- quality improvement
- chronic obstructive pulmonary disease
- primary care
- palliative care
- oxidative stress
- peritoneal dialysis
- prognostic factors
- cancer therapy
- gene expression
- dna methylation
- drug delivery
- patient reported outcomes
- patient reported
- health insurance
- allergic rhinitis
- affordable care act