A versatile papaya mosaic virus (PapMV) vaccine platform based on sortase-mediated antigen coupling.
Ariane ThérienMikaël BédardDamien CarignanGervais RiouxLouis Gauthier-LandryMarie-Ève Laliberté-GagnéMarilène BolducPierre SavardDenis LeclercPublished in: Journal of nanobiotechnology (2017)
This technology will allow the development of vaccines harbouring long peptides containing several B and/or T cell epitopes that can contribute to a broad and robust protection from infection. The design can be fast, versatile and can be adapted to the development of vaccines for many infectious diseases as well as cancer vaccines.