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A versatile papaya mosaic virus (PapMV) vaccine platform based on sortase-mediated antigen coupling.

Ariane ThérienMikaël BédardDamien CarignanGervais RiouxLouis Gauthier-LandryMarie-Ève Laliberté-GagnéMarilène BolducPierre SavardDenis Leclerc
Published in: Journal of nanobiotechnology (2017)
This technology will allow the development of vaccines harbouring long peptides containing several B and/or T cell epitopes that can contribute to a broad and robust protection from infection. The design can be fast, versatile and can be adapted to the development of vaccines for many infectious diseases as well as cancer vaccines.
Keyphrases
  • infectious diseases
  • papillary thyroid
  • high throughput
  • squamous cell carcinoma
  • room temperature
  • amino acid
  • single cell
  • lymph node metastasis