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Evaluation of protein kinase D auto-phosphorylation as biomarker for NLRP3 inflammasome activation.

Diane HeiserJoëlle RubertAdeline UnterreinerClaudine MaurerMarion KamkeUrsula BodendorfChristopher J FaradyBen RoedigerFrédéric Bornancin
Published in: PloS one (2021)
Although PKD and NLRP3 become functionally interconnected during NLRP3 activation, the promiscuous reactivity of PKD challenges its potential use for tracing the NLRP3 inflammasome pathway.
Keyphrases
  • nlrp inflammasome
  • protein kinase
  • polycystic kidney disease