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Noise robustness and metabolic load determine the principles of central dogma regulation.

Teresa W LoHan James ChoiDean HuangPaul A Wiggins
Published in: bioRxiv : the preprint server for biology (2024)
Fitness maximization predicts protein overabundance, a transcriptional floor, and the balancing of transcription and translation.
Keyphrases
  • transcription factor
  • body composition
  • physical activity
  • gene expression
  • air pollution
  • protein protein
  • amino acid
  • binding protein
  • small molecule