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Clinical outcomes of pediatric patients with autism spectrum disorder and other neurodevelopmental disorders and intracranial germ cell tumors.

Kevin X LiuRoshan V SethiMargaret B PulsiferAlissa M D'GamaBeverly LaVallyDavid H EbbNancy J TarbellTorunn I YockShannon M MacDonald
Published in: Pediatric blood & cancer (2021)
Our study found an ASD prevalence in the pure germinoma cohort more than threefold greater than the national prevalence, suggesting an association between ASD and pure germinomas. Furthermore, patients with NDD and NGGCT had worse PFS, possibly due to fewer patients with NDD receiving CSI. Future prospective studies with larger cohorts are needed to examine associations between NDDs and IGCTs, and further characterize outcomes for patients with NDDs and IGCTs.
Keyphrases
  • germ cell
  • autism spectrum disorder
  • risk factors
  • attention deficit hyperactivity disorder
  • intellectual disability
  • adipose tissue
  • working memory
  • congenital heart disease
  • optical coherence tomography