Should sulfonylurea be discontinued or maintained at the lowest dose when starting ipragliflozin? A multicenter observational study in Japanese patients with type 2 diabetes.
Kiyohiko TakahashiKyu Yong ChoAkinobu NakamuraAika MiyaArina MiyoshiChiho YamamotoHiroshi NomotoHirokatsu NiwaKiyohito TakahashiNaoki MandaYoshio KuriharaShin AokiYoichi M ItoTatsuya AtsumiHideaki MiyoshiPublished in: Journal of diabetes investigation (2018)
The purpose of using ipragliflozin should be considered when making the decision to discontinue or maintain sulfonylurea at the lowest dose. Furthermore, low high-density lipoprotein cholesterol level, low dose of sulfonylurea and younger age were possible markers to not show worsening of glycemic control by discontinuing sulfonylurea.