Blood-based screening for HPV-associated cancers.

Dipon DasShun HirayamaLing AyeMichael E BryanSaskia NaegeleBrian ZhaoVasileios EfthymiouJulia MendelAdam S FischLea KröllerBirgitta E MichelsTim WaterboerJeremy D RichmonViktor AdalsteinssonMichael S LawrenceMatthew Gordon CrowsonA John IafrateDaniel L Faden

Published in: medRxiv : the preprint server for health sciences (2024)

We demonstrate accurate blood-based detection of HPV-associated cancers with lead times up to 10 years before clinical cancer diagnosis and in doing so, highlight the enormous potential of ctDNA-based cancer screening.

Keyphrases

papillary thyroid
squamous cell
high grade
lymph node metastasis
squamous cell carcinoma
mass spectrometry
label free
cervical cancer screening
sensitive detection