Fluorescence Lifetime-Based Tumor Contrast Enhancement Using an EGFR Antibody-Labeled Near-Infrared Fluorophore.

Rahul PalHoman KangHak Soo ChoiAnand T N Kumar

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)

Our data suggest that FLT can significantly enhance tumor contrast using fluorescently labeled antibodies, thereby accelerating the efficient clinical application of these probes for margin assessment in image-guided surgery and for highly specific detection of tumor receptors in vivo.

Keyphrases

magnetic resonance
small cell lung cancer
tyrosine kinase
minimally invasive
single molecule
acute myeloid leukemia
small molecule
pet imaging
computed tomography
coronary artery bypass
coronary artery disease
fluorescent probe
artificial intelligence
data analysis
energy transfer
real time pcr