Docetaxel Enhances Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Mediated Apoptosis in Prostate Cancer Cells via Epigenetic Gene Regulation by Enhancer of Zeste Homolog 2.

Won Hyeok Lee Seong Cheol Kim Song Hee Kim Ji Hyung Yoon Kyung Hyun Moon Sang Hyeon Cheon Teakmin Kwon Young Min Kim Jeong Woo Park Sang Hun Lee Jeong Min Lee Sungchan Park Benjamin I Chung

Published in: The world journal of men's health (2023)

elevation of DR4 through epigenetic regulation by EZH2. To improve the efficacy of TRAIL for PCa treatment, adding docetaxel or EZH2 inhibitors to TRAIL may be promising.

Keyphrases

long non coding rna
oxidative stress
dna methylation
locally advanced
gene expression
rheumatoid arthritis
endoplasmic reticulum stress
transcription factor
cell cycle arrest
binding protein
combination therapy
editorial comment
drug induced