Free-Radical-Promoted Dehydrogenative Coupling of Polyfluorinated Alcohol with Quinone, Chromone, and Coumarin.

Jingping LiuDan YuYong YangHuichao YouMinzhi SunYaxin WangXu ShenZhong-Quan Liu

Published in: Organic letters (2020)

A free-radical-mediated dehydrogenative cross-coupling reaction of polyfluorinated alcohol with quinone, coumarin, and chromone was developed. It provides a sustainable and practical strategy for installation of fluorine atom into organic molecules by using polyfluorinated alcohols.

Keyphrases

fluorescent probe
alcohol consumption
electron transfer
positron emission tomography
molecular dynamics
room temperature
computed tomography
pet imaging