Berberine Inhibits the Apoptosis-Induced Metastasis by Suppressing the iPLA2/LOX-5/LTB4 Pathway in Hepatocellular Carcinoma.

Yawei ZhaoKan HeHuilin ZhengMadi SunTongfei ShiXiao ZhengDan ShaoHansi ZhangFengying GuanJing LiLi Chen

Published in: OncoTargets and therapy (2020)

Our study sheds light on a novel anti-metastasis strategy that the combination of Berberine and chemotherapy may prevent the chemotherapy-induced metastasis in HCC.

Keyphrases

chemotherapy induced
oxidative stress
endoplasmic reticulum stress
high glucose
cell death
radiation therapy
endothelial cells
cell proliferation
drug induced