Recurrent eosinophilic granuloma involving maxilla and mandible in an adult male: an unusual case report.
Xudong XieJ WangY DingPublished in: Australian dental journal (2021)
Langerhans' cell histiocytosis (LCH) is a disease spectrum characterized by the intense infiltration/accumulation of Langerhans' cells in the affected tissues. Eosinophilic granuloma is the mildest form of LCH which mainly affects the skull, mandible, ribs and femur in children and young adults but rarely occurs in the maxilla. Here, we describe an unusual case of eosinophilic granuloma affecting the tissues adjacent to tooth #25 and tooth #46 (FDI numbering system) in a 35-year-old male. Although lesions underwent clinical remission after local radiotherapy, a new lesion appeared 11 months after initial therapy in tooth #18, indicating recurrence of eosinophilic granuloma. Subsequently, the patient was treated with corticosteroid therapy, achieved remission and is disease free after 3 years of follow-up.
Keyphrases
- case report
- young adults
- chronic rhinosinusitis
- gene expression
- induced apoptosis
- disease activity
- early stage
- cell therapy
- single cell
- cell cycle arrest
- radiation therapy
- ulcerative colitis
- rheumatoid arthritis
- radiation induced
- bone mineral density
- locally advanced
- cell death
- body composition
- mesenchymal stem cells
- free survival
- newly diagnosed
- pi k akt
- finite element