Diagnostic challenges in patients with temporal lobe seizures and features of autoimmune limbic encephalitis.
Fatme Seval IsmailMarianna SpatolaFriedrich G WoermannStoyan PopkirovJohannes JungilligensChristian G BienJörg WellmerUwe SchlegelPublished in: European journal of neurology (2021)
In patients with temporal lobe seizures and additional limbic signs, 17% had neuronal Abs affirming ALE diagnosis. Mediotemporal MRI changes were found in all Ab-positive cases and had a positive likelihood ratio of 2.11 (95% confidence interval 1.51-2.95).