Efficacy and safety of withholding antimicrobial therapy in children with cancer, fever, and neutropenia, with a demonstrated viral respiratory infection: a randomized clinical trial.
Juan P TorresCarolina IbañezRomina ValenzuelaSalome RiveraVeronica De la MazaMilena VillarroelPaulina CoriaVeronica ContardoAna M ÁlvarezCarmen M ZubietaValentina GutierrezKaren DucasseDaniela MartínezMaria E SantolayaPublished in: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases (2024)
We validated the strategy of withdrawal antimicrobial therapy in children with FN and viral respiratory tract infection based on clinical and microbiological/molecular diagnostic criteria. This will enable advances in antimicrobial stewardship strategies with a possible future impact on antimicrobial resistance.