Efficacy of RCI001 as a therapeutic candidate of dry eye disease in a modified mixed dry eye model.

Young-Ho JungYoung Ah KuJayoon MoonSeunghoon KimJin Suk RyuChang Ho YoonMyung Hee ChungYong Ho KimMee Kum KimDong Hyun Kim

Published in: Eye and vision (London, England) (2024)

Topical RCI001 showed excellent therapeutic effects in environmental DED models by stimulating tear secretion, modulating oxidative stress and improving corneal epithelial healing compared to 1% PDE and 5% Lifitegrast.

Keyphrases

oxidative stress
wound healing
signaling pathway
dna damage
ischemia reperfusion injury
climate change
heat stress