Individual patient data meta-analysis estimates the minimal detectable change of the Geriatric Depression Scale-15.

Nadia P González-DomínguezYin WuSuiqiong FanBrooke LevisYing SunSimon GilbodyJohn P A IoannidisDaphna HarelSimone N VigodSarah MarkhamRoy C ZiegelsteinPim CuijpersScott B PattenJill T BoruffBrett D ThombsAndrea Benedettinull null

Published in: Journal of clinical epidemiology (2024)

The MDC95 was 3.81 points and MDC67 was 1.95 points. MDC95 increased with the proportion of participants with major depression. Results can be used to evaluate individual changes in depression symptoms and as a threshold for assessing minimal clinical important difference estimates.

Keyphrases

systematic review
sleep quality
depressive symptoms
case report
meta analyses
electronic health record
big data
artificial intelligence