Reversible hypoxic brain injury: the penumbra conundrum of Grinker.
Shiva BalanKartik GuptaParthiban BalasundaramRanveer JadonPublished in: BMJ case reports (2019)
A female patient, aged 61 years, presented to us with a 3-day history of fever and altered sensorium. She was discharged from another hospital 1 week back where she was admitted for community-acquired pneumonia. She was put on mechanical ventilation for threatened airway and her magnetic resonance brain imaging showed evidence of delayed posthypoxic leucoencephalopathy, also known as Grinker's myelinopathy. She was discharged 1 month later, on room air with a tracheostomy tube in situ. On follow-up after 5 months, she was ambulating with support and carried out activities of daily living independently.
Keyphrases
- mechanical ventilation
- brain injury
- community acquired pneumonia
- magnetic resonance
- cerebral ischemia
- subarachnoid hemorrhage
- acute respiratory distress syndrome
- intensive care unit
- high resolution
- respiratory failure
- case report
- resting state
- healthcare
- white matter
- contrast enhanced
- extracorporeal membrane oxygenation
- acute care
- adverse drug
- clinical trial
- fluorescence imaging
- magnetic resonance imaging
- photodynamic therapy
- electronic health record
- drug induced