Aversion-resistant fentanyl self-administration in mice.

Published in: Psychopharmacology (2020)

Mice will respond for and consume oral fentanyl in both a two-bottle choice and an operant response task. Quinine is detectable in fentanyl but mice will continue to respond for and consume fentanyl with quinine in both paradigms. These data support the use of these models in behavioral studies of compulsive-like opioid use.

Keyphrases

high fat diet induced
type diabetes
wild type
obsessive compulsive disorder
adipose tissue
electronic health record
metabolic syndrome