Tuberculosis in children and adolescents with rheumatic diseases using biologic agents: an integrative review.
Lenita de Melo LimaRafaela Baroni AurilioAdriana Rodrigues FonsecaAna Alice Amaral Ibiapina ParenteMaria de Fátima Bazhuni Pombo MarchClemax Couto Sant'AnnaPublished in: Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo (2023)
The study revealed a low rate of active TB in pediatric patients using biologic therapy. Screening for LTBI before initiating biologics should be done in all patients, and treatment, in cases of positive screening, plays a critical role in preventing progression to TB disease.