Incidence of acute kidney injury (AKI) and its impact on patient outcomes among adult hospitalized patients with carbapenem-resistant Gram-negative infections who received targeted treatment with a newer β-lactam or β-lactam/β-lactamase inhibitor-, polymyxin- or aminoglycoside-containing regimen.
Thomas P LodiseEmre YucelEngels N ObiAlexandre H WatanabeBrian H NathansonPublished in: The Journal of antimicrobial chemotherapy (2023)
The AKI incidence was highest among PB patients and patients with AKI had worse outcomes. Healthcare systems should consider minimizing the use of antibiotics that augment AKI risk as a measure to improve outcomes in patients with CR-GNIs.
Keyphrases
- acute kidney injury
- gram negative
- multidrug resistant
- cardiac surgery
- healthcare
- end stage renal disease
- acinetobacter baumannii
- risk factors
- ejection fraction
- drug resistant
- newly diagnosed
- escherichia coli
- peritoneal dialysis
- prognostic factors
- klebsiella pneumoniae
- pseudomonas aeruginosa
- risk assessment
- heavy metals
- type diabetes
- case report
- metabolic syndrome
- health information
- drug delivery
- glycemic control
- adipose tissue
- skeletal muscle
- insulin resistance
- weight loss