Glutamine synthetase promotes tumor invasion in hepatocellular carcinoma through mediating epithelial-mesenchymal transition.

Peng LiuDi LuAbdulahad Abdulrab Mohammed Al-AmeriXuyong WeiSunbin LingJie LiHai ZhuHaiyang XieLiming ZhuShusen ZhengXiao Xu

Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2020)

GS is a useful biomarker for HCC diagnosis, especially for AFP-negative patients. In addition, GS affects HCC metastasis through mediating epithelial-mesenchymal transition.

Keyphrases

epithelial mesenchymal transition
end stage renal disease
transforming growth factor
ejection fraction
signaling pathway
newly diagnosed
chronic kidney disease
prognostic factors
cell migration