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Anti-Allodynic Effects of Polydeoxyribonucleotide in an Animal Model of Neuropathic Pain and Complex Regional Pain Syndrome.

Sung Hyun LeeSie Hyeon YooHae Jin LeeDonggyu HanJiyoung LeeSeung Hwan JeonEun Ah ChoHue Jung Park
Published in: Journal of Korean medical science (2020)
SC administration of PDRN results in the attenuation of allodynia and activation of astrocytes in neuropathic pain or CRPS models. We propose that PDRN can have significant potential advantages in neuropathic pain treatment.
Keyphrases
  • neuropathic pain
  • spinal cord
  • spinal cord injury
  • combination therapy
  • risk assessment
  • human health
  • climate change
  • replacement therapy