Single-cell whole exome and targeted sequencing in NPM1/FLT3 positive pediatric acute myeloid leukemia.
Christiane WalterChristian PozzoriniKatarina ReinhardtRobert GeffersZhenyu XuDirk ReinhardtNils von NeuhoffHelmut HanenbergPublished in: Pediatric blood & cancer (2017)
In summary, our study demonstrated that single-cell WES combined with bulk DNA TS is a promising tool set for detecting AML subclones and possibly LSCs.