Refining the Intraoperative Identification of Suspected High-Grade Glioma Using a Surgical Fluorescence Biomarker: GALA BIDD Study Report.

Colin WattsAlimu Dayimu Tomasz MatysKeyoumars AshkanStephen John Price Michael D JenkinsonGail DoughtonClaire MatherGemma YoungWendi QianKathreena M Kurian

Published in: Journal of personalized medicine (2023)

In patients where there is clinical suspicion, visible 5-ALA fluorescence has clinical utility as an intraoperative surgical biomarker of high-grade gliomas and can aid surgical decision-making and sampling. Further studies assessing the use of 5-ALA to assess malignant transformation in all diffuse gliomas may be valuable.

Keyphrases

high grade
low grade
end stage renal disease
decision making
single molecule
ejection fraction
newly diagnosed
peritoneal dialysis
chronic kidney disease
energy transfer
patient reported