SARS-CoV-2 viral spike G614 mutation exhibits higher case fatality rate.

Published in: International journal of clinical practice (2020)

These results imply that G614 is a more pathogenic strain of SARS-CoV-2, which may influence vaccine design. The prevalence of this form of the virus should also be included in epidemiologic models predicting the COVID-19 health burden and fatality over time in specific regions. Physicians should be aware of this characteristic of the virus to anticipate the clinical course of infection.

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respiratory syndrome coronavirus
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