Serum-free medium and hypoxic preconditioning synergistically enhance the therapeutic effects of mesenchymal stem cells on experimental renal fibrosis.

Naoki IshiuchiAyumu NakashimaShigehiro DoiRyo KanaiSatoshi MaedaShinya TakahashiMasataka NagaoTakao Masaki

Published in: Stem cell research & therapy (2021)

These results indicate that administration of ex vivo-expanded, hypoxia-preconditioned SF-MSCs may be a useful cell therapy to prevent renal fibrosis.

Keyphrases

cell therapy
mesenchymal stem cells
umbilical cord
bone marrow
stem cells
endothelial cells
ischemia reperfusion injury
liver fibrosis
blood brain barrier
subarachnoid hemorrhage