Trends in Feminizing Hormone Therapy for Transgender Patients, 2006-2017.
Adam J RoseJaclyn M W HughtoMichael S DunbarEmily K QuinnMadeline DeutschJamie FeldmanAsa E RadixJoshua D SaferJillian C ShipherdJulie ThompsonGuneet K JasujaPublished in: Transgender health (2023)
Combination therapy with estrogen and spironolactone may help some transgender women achieve desired results. We used two databases, OptumLabs ® Data Warehouse (OLDW) and Veterans Health Administration (VHA), to examine trends in feminizing therapy. We included 3368 transgender patients from OLDW and 3527 from VHA, all of whom received estrogen, spironolactone, or both between 2006 and 2017. In OLDW, the proportion receiving combination therapy increased from 47% to 75% during this period. Similarly, in VHA, the proportion increased from 39% to 69% during this period. We conclude that the use of combination hormone therapy has become much more common over the past decade.
Keyphrases
- combination therapy
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- healthcare
- prognostic factors
- peritoneal dialysis
- type diabetes
- pregnant women
- mental health
- patient reported outcomes
- electronic health record
- machine learning
- risk assessment
- big data
- adipose tissue
- men who have sex with men
- social media
- bone marrow
- deep learning
- human health
- breast cancer risk