House dust mite impairs antiviral response in asthma exacerbation models through its effects on TLR3.
Hamid AkbarshahiM MenzelS RamuI Mahmutovic PerssonL BjermerLena UllerPublished in: Allergy (2018)
Direct effects of allergens such as HDM on PRRs can present as potential mechanism for defective antiviral airway responses. Accordingly, therapeutic measures targeting inhibitory effects of allergens on antiviral PRRs may find use as a strategy to boost antiviral response and ameliorate exacerbations in asthmatic patients.
Keyphrases
- chronic obstructive pulmonary disease
- end stage renal disease
- lung function
- newly diagnosed
- ejection fraction
- chronic kidney disease
- toll like receptor
- peritoneal dialysis
- prognostic factors
- allergic rhinitis
- human health
- cancer therapy
- air pollution
- patient reported outcomes
- climate change
- drug delivery
- nuclear factor
- patient reported