Combination of downregulating FEN1 and PD-1 blockade enhances antitumor activity of CD8+ T cells against HNSCC cells in vitro.

Xiangjian WangShenjie XuTao FuYang WuWeilian Sun

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2023)

These findings might offer a potential combined strategy for patients resistant to anti-PD therapy via combining FEN1 knockdown and PD-1 blockade.

Keyphrases

end stage renal disease
induced apoptosis
ejection fraction
chronic kidney disease
peritoneal dialysis
stem cells
oxidative stress
risk assessment
patient reported outcomes
cell therapy
patient reported
smoking cessation