Ex vivo observation of granulocyte activity during thrombus formation.
Daria S MorozovaAlexey A MartyanovSergei I ObydennyiJulia-Jessica D KorobkinAlexey V SokolovEkaterina V ShamovaIrina V GorudkoAnna L KhorevaAnna ShcherbinaMikhail A PanteleevAnastasia N SveshnikovaPublished in: BMC biology (2022)
We have developed an ex vivo experimental model applicable for observation of granulocyte activity in thrombus formation. Using the proposed setting, we observed a reduction of motility of granulocytes of patients with WAS. We suggest that our ex vivo approach should be useful both for basic and for clinical research.