Molecular characterization of an outbreak-involved Bacillus anthracis strain confirms the spillover of anthrax from West Africa.

Shuchao WangRoland SulukuMohamed B JallohAhmed F SambaBaogui JiangYubiao XieDoris HardingMengyao ZhangFoday SahrMahmud E SesayJames S SquireMohamed A VandiMoinina N KallonShoufeng ZhangRongliang HuYuee ZhaoZhiqiang Mi

Published in: Infectious diseases of poverty (2024)

We successfully identified a large-scale anthrax outbreak in Sierra Leone. The causative isolate of B. anthracis, BaSL2022, phylogenetically bridged other lineages in A.Br.153 clade and neighboring genetic groups, A.Br.144 and A.Br.148, eventually confirming the spillover of anthrax from West Africa. Given the wide dissemination of B. anthracis spores, it is highly advisable to effectively monitor the potential reoccurrence of anthrax outbreaks and to launch campaigns to improve public awareness regarding anthrax in Sierra Leone.

Keyphrases

healthcare
mental health
gene expression
emergency department
risk assessment
dna methylation
adverse drug