Multivariate analysis of metabolic parameters and optimization of antibody production using high cell density hybridoma in hollow fiber bioreactors.
Chi-Hsien LiuYi-Xin LiuMonika KumariWei-Chi WuPublished in: Biotechnology letters (2019)
The single-use HFBs could provide the advantages including high cell density, low shear stress, and continuous antibody production.