The efficacy and safety of anti-interleukin-6 receptor monoclonal blockade in a renal transplant patient with Castleman disease: early post-transplant outcome.
Masatoshi MatsunamiYoshifumi UbaraKeiichi SumidaYoichi OshimaMasahiko OguroKazuya KinoshitaKiho TanakaYuki NakamuraKeiichi KinowakiKenichi OhashiTakeshi FujiiTakuro IgawaYasuharu SatoYasuo IshiiPublished in: BMC nephrology (2018)
To our knowledge, this is the second reported case of an MCD patient with ESRD who underwent successful KTx. TCZ safely supported the patient during the perioperative period, and this drug may be useful for blocking the generation of donor-specific antibodies and reducing the risk of rejection episodes. KTx in combination with TCZ is thus considered a viable treatment option for ESRD due to MCD.