CeO 2 -Azacrown Conjugate as a Nanoplatform for Combined Radiopharmaceuticals.
Sofia KhabirovaGleb Yu AleshinTatiana PlakhovaAnastasia ZubenkoAnna A ShchukinaOlga FedorovaAleksey AverinEkaterina BelovaElena BazarkinaKristina KvashninaStepan KalmykovPublished in: Nanomaterials (Basel, Switzerland) (2022)
This study is one of the first attempts to assess CeO 2 nanoparticles as a nanoplatform for radiopharmaceuticals with radionuclides. The process of functionalization using a bifunctional azacrown ligand is described, and the resulting conjugates are characterized by IR and Raman spectroscopy. Their complexes with 207 Bi show a high stability in medically relevant media, thus encouraging the further study of these conjugates in vivo as potential combined radiopharmaceuticals.